In vivo detection of EGFRvIII in glioblastoma via perfusion magnetic resonance imaging signature consistent with deep peritumoral infiltration: the φ index

PURPOSE: The epidermal growth factor receptor variant III (EGFRvIII) mutation has been considered a driver mutation and therapeutic target in glioblastoma, the most common and aggressive brain cancer. Currently, detecting EGFRvIII requires postoperative tissue analyses, which are ex vivo and unable...

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Publicado en:Clin Cancer Res
Autores principales: Bakas, Spyridon, Akbari, Hamed, Pisapia, Jared, Martinez-Lage, Maria, Rozycki, Martin, Rathore, Saima, Dahmane, Nadia, O’Rourke, Donald M., Davatzikos, Christos
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559313/
https://ncbi.nlm.nih.gov/pubmed/28428190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1871
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