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Immune-related tumor response dynamics in melanoma patients treated with pembrolizumab: Identifying markers for clinical outcome and treatment decisions

PURPOSE: Characterize tumor burden dynamics during PD-1 inhibitor therapy and investigate the association with overall survival (OS) in advanced melanoma. EXPERIMENTAL DESIGN: The study included 107 advanced melanoma patients treated with pembrolizumab. Tumor burden dynamics were assessed on serial...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Nishino, Mizuki, Giobbie-Hurder, Anita, Manos, Michael P., Bailey, Nancy D., Buchbinder, Elizabeth I., Ott, Patrick A., Ramaiya, Nikhil H., Hodi, F. Stephen
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559305/
https://ncbi.nlm.nih.gov/pubmed/28592629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0114
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