Inhibition of Soluble Epoxide Hydrolase Alleviated Atherosclerosis by Reducing Monocyte Infiltration in Ldlr(−/−) Mice

RATIONALE: Circulating monocytes play pivotal roles in chronic inflammatory diseases. Epoxyeicosatrienoic acids (EETs), metabolites of arachidonic acid, are known to have anti-inflammatory effects and are hydrolyzed by soluble epoxide hydrolase (sEH). OBJECTIVE: We aimed to investigate the effect of...

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Udgivet i:J Mol Cell Cardiol
Main Authors: Li, Dan, Liu, Yajin, Zhang, Xu, Lv, Huizhen, Pang, Wei, Sun, Xiaoli, Gan, Li-Ming, Hammock, Bruce D, Ai, Ding, Zhu, Yi
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559083/
https://ncbi.nlm.nih.gov/pubmed/27496380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.08.001
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