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Design and synthesis of theranostic antibiotic nanodrugs that display enhanced antibacterial activity and luminescence

We report the modular formulation of ciprofloxacin-based pure theranostic nanodrugs that display enhanced antibacterial activities, as well as aggregation-induced emission (AIE) enhancement that was successfully used to image bacteria. The drug derivatives, consisting of ciprofloxacin, a perfluoroar...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Xie, Sheng, Manuguri, Sesha, Proietti, Giampiero, Romson, Joakim, Fu, Ying, Inge, A. Ken, Wu, Bin, Zhang, Yang, Häll, Daniel, Ramström, Olof, Yan, Mingdi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559051/
https://ncbi.nlm.nih.gov/pubmed/28743748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708556114
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