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Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model

Mitochondrial dysfunction has been associated with obesity and metabolic disorders. However, whether mitochondrial perturbation in a single tissue influences mitochondrial function and metabolic status of another distal tissue remains largely unknown. We analyzed the nonautonomous role of muscular m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Song, Wei, Owusu-Ansah, Edward, Hu, Yanhui, Cheng, Daojun, Ni, Xiaochun, Zirin, Jonathan, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559048/
https://ncbi.nlm.nih.gov/pubmed/28739899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708037114
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