Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association

Many enveloped viruses encode a matrix protein. In the influenza A virus, the matrix protein M1 polymerizes into a rigid protein layer underneath the viral envelope to help enforce the shape and structural integrity of intact viruses. The influenza virus M1 is also known to mediate virus budding as...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Wenting, Zheng, Wenjie, Toh, Yukimatsu, Betancourt-Solis, Miguel A., Tu, Jiagang, Fan, Yanlin, Vakharia, Vikram N., Liu, Jun, McNew, James A., Jin, Meilin, Tao, Yizhi J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559005/
https://ncbi.nlm.nih.gov/pubmed/28739952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701747114
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