Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

Since neutralizing antibodies (NAb) targeting the human cytomegalovirus (HCMV) pentamer complex (PC) potently block HCMV host cell entry, anti-PC NAb induction is thought to be important for a vaccine formulation to prevent HCMV infection. By developing a vaccine strategy based on soluble PC protein...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Chiuppesi, Flavia, Wussow, Felix, Scharf, Louise, Contreras, Heidi, Gao, Han, Meng, Zhuo, Nguyen, Jenny, Barry, Peter A., Bjorkman, Pamela J., Diamond, Don J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558987/
https://ncbi.nlm.nih.gov/pubmed/28813507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183377
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