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Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms

Zebrafish morphants of osm-3/kif17, a kinesin-2 family member and intraflagellar transport motor, have photoreceptor outer segments that are dramatically reduced in number and size. However, two genetic mutant lines, osm-3/kif17(sa0119) and osm-3/kif17(sa18340), reportedly lack any observable morpho...

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Foilsithe in:Dev Biol
Main Authors: Lewis, Tylor R., Kundinger, Sean R., Pavlovich, Amira L., Bostrom, Jonathan R., Link, Brian A., Besharse, Joseph C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558849/
https://ncbi.nlm.nih.gov/pubmed/28341548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.03.019
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