Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

BACKGROUND: Radiotherapy has been used increasingly to treat primary hepatocellular carcinoma. Clinically, the main cause of radiotherapy failure is cellular radioresistance, conferred via glycolytic metabolism. Our previous study demonstrated that Girdin is upregulated in primary hepatocellular car...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Yu, Li, Sun, Yifan, Li, Jingjing, Wang, Yan, Zhu, Yuxing, Shi, Yong, Fan, Xiaojun, Zhou, Jianda, Bao, Ying, Xiao, Jie, Cao, Ke, Cao, Peiguo
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558715/
https://ncbi.nlm.nih.gov/pubmed/28810896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0580-7
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