Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

BACKGROUND: Radiotherapy has been used increasingly to treat primary hepatocellular carcinoma. Clinically, the main cause of radiotherapy failure is cellular radioresistance, conferred via glycolytic metabolism. Our previous study demonstrated that Girdin is upregulated in primary hepatocellular car...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yu, Li, Sun, Yifan, Li, Jingjing, Wang, Yan, Zhu, Yuxing, Shi, Yong, Fan, Xiaojun, Zhou, Jianda, Bao, Ying, Xiao, Jie, Cao, Ke, Cao, Peiguo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558715/
https://ncbi.nlm.nih.gov/pubmed/28810896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0580-7
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