Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

BACKGROUND: Radiotherapy has been used increasingly to treat primary hepatocellular carcinoma. Clinically, the main cause of radiotherapy failure is cellular radioresistance, conferred via glycolytic metabolism. Our previous study demonstrated that Girdin is upregulated in primary hepatocellular car...

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Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Yu, Li, Sun, Yifan, Li, Jingjing, Wang, Yan, Zhu, Yuxing, Shi, Yong, Fan, Xiaojun, Zhou, Jianda, Bao, Ying, Xiao, Jie, Cao, Ke, Cao, Peiguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558715/
https://ncbi.nlm.nih.gov/pubmed/28810896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0580-7
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