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Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

Cells adapt to an exposure to xenobiotics by upregulating the biosynthesis of proteins involved in xenobiotic metabolism. This is achieved largely via activation of cellular xenosensors that modulate gene expression. Biotransformation of xenobiotics frequently comes with the generation of reactive o...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Klotz, Lars-Oliver, Steinbrenner, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558470/
https://ncbi.nlm.nih.gov/pubmed/28818793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.015
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