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The GTPase regulatory proteins Pix and Git control tissue growth via the Hippo pathway

The Salvador-Warts-Hippo (Hippo) pathway is a conserved regulator of organ size and is deregulated in human cancers [1]. In epithelial tissues, the Hippo pathway is regulated by fundamental cell biological properties, such as polarity and adhesion, and coordinates these with tissue growth [2–4]. Des...

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Publicat a:Curr Biol
Autors principals: Dent, Lucas G., Poon, Carole L.C., Zhang, Xiaomeng, Degoutin, Joffrey L., Tipping, Marla, Veraksa, Alexey, Harvey, Kieran F.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558436/
https://ncbi.nlm.nih.gov/pubmed/25484297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.041
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