Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-632

The structures of 12 new “enantiomeric”-like abyssomicin metabolites (abyssomicins M–X) from Streptomyces sp. LC-6-2 are reported. Of this set, the abyssomicin W (11) contains an unprecedented 8/6/6/6 tetracyclic core, while the bicyclic abyssomicin X (12) represents the first reported naturally occ...

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Udgivet i:J Nat Prod
Main Authors: Wang, Xiachang, Elshahawi, Sherif I., Cai, Wenlong, Zhang, Yinan, Ponomareva, Larissa V., Chen, Xiabin, Copley, Gregory C., Hower, James C., Zhan, Chang-Guo, Parkin, Sean, Rohr, Jürgen, Van Lanen, Steven G., Shaaban, Khaled A., Thorson, Jon S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558431/
https://ncbi.nlm.nih.gov/pubmed/28358212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b00108
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