Serum-derived extracellular vesicles (EVs) impact on vascular remodeling and prevent muscle damage in acute hind limb ischemia

Serum is an abundant and accessible source of circulating extracellular vesicles (EVs). Serum-EV (sEV) pro-angiogenic capability and mechanisms are herein analyzed using an in vitro assay which predicts sEV angiogenic potential in vivo. Effective sEVs (e-sEVs) also improved vascular remodeling and p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Cavallari, Claudia, Ranghino, Andrea, Tapparo, Marta, Cedrino, Massimo, Figliolini, Federico, Grange, Cristina, Giannachi, Valentina, Garneri, Paolo, Deregibus, Maria Chiara, Collino, Federica, Rispoli, Pietro, Camussi, Giovanni, Brizzi, Maria Felice
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557987/
https://ncbi.nlm.nih.gov/pubmed/28811546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08250-0
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