Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals

Morbidly obese patients exhibit impaired secretion of gut hormones that may contribute to the development of obesity. After bariatric surgery there is a dramatic increase in gut hormone release. In this study, gastric and duodenal tissues were endoscopically collected from lean, and morbidly obese s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wölnerhanssen, Bettina K., Moran, Andrew W., Burdyga, Galina, Meyer-Gerspach, Anne Christin, Peterli, Ralph, Manz, Michael, Thumshirn, Miriam, Daly, Kristian, Beglinger, Christoph, Shirazi-Beechey, Soraya P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557953/
https://ncbi.nlm.nih.gov/pubmed/28811552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08487-9
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