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Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in Trypanosoma brucei

Leucine aminopeptidase (LAP) is found in all kingdoms of life and catalyzes the metal-dependent hydrolysis of the N-terminal amino acid residue of peptide or amino acyl substrates. LAPs have been shown to participate in the N-terminal processing of certain proteins in mammalian cells and in homologo...

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Publicado en:mSphere
Main Authors: Timm, Jennifer, Valente, Maria, García-Caballero, Daniel, Wilson, Keith S., González-Pacanowska, Dolores
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557676/
https://ncbi.nlm.nih.gov/pubmed/28815215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00226-17
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