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Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed at Atomic Detail
Synaptotagmin (Syt) is a membrane-associated protein involved in vesicle fusion through the SNARE complex that is found throughout the human body in 17 different isoforms. These isoforms have two membrane-binding C2 domains, which sense Ca(2+) and thereby promote anionic membrane binding and lead to...
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| Publicado en: | Biochemistry |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5557660/ https://ncbi.nlm.nih.gov/pubmed/27997124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00468 |
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