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Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops

Claudins (Cldns) are transmembrane tight junction (TJ) proteins that paracellularly seal endo- and epithelial barriers by their interactions within the TJs. However, the mechanisms allowing TJ remodeling while maintaining barrier integrity are largely unknown. Cldns and occludin are heterophilically...

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Pubblicato in:PLoS One
Autori principali: Gehne, Nora, Lamik, Agathe, Lehmann, Martin, Haseloff, Reiner F., Andjelkovic, Anuska V., Blasig, Ingolf E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557494/
https://ncbi.nlm.nih.gov/pubmed/28813441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182106
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