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Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials

BACKGROUND AND OBJECTIVE: Chronic Low Back Pain (CLBP) is very common, with a lifetime prevalence between 51% and 80%. In majority, it is nonspecific in nature and multifactorial in etiology. Pregabalin (PG) and Gabapentin (GB) are gabapentinoids that have demonstrated benefit in neuropathic pain co...

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Pubblicato in:PLoS Med
Autori principali: Shanthanna, Harsha, Gilron, Ian, Rajarathinam, Manikandan, AlAmri, Rizq, Kamath, Sriganesh, Thabane, Lehana, Devereaux, Philip J., Bhandari, Mohit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557428/
https://ncbi.nlm.nih.gov/pubmed/28809936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002369
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