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Isolation, structure elucidation, and synthesis of antiplasmodial quinolones from Crinum firmifolium

Antiplasmodial bioassay guided fractionation of a Madagascar collection of Crinum firmifolium led to the isolation of seven compounds. Five of the seven compounds were determined to be 2-alkylquinolin-4(1H)-ones with varying side chains. Compounds 1 and 4 were determined to be known compounds with r...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Presley, Christopher C., Du, Yongle, Dalal, Seema, Merino, Emilio F., Butler, Joshua H., Rakotonandrasana, Stéphan, Rasamison, Vincent E., Cassera, Maria B., Kingston, David G. I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557408/
https://ncbi.nlm.nih.gov/pubmed/28648491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.06.017
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