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Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice

BACKGROUND: Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced CTL responses and improves prevention of tumour growth in animal models compar...

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Библиографические подробности
Опубликовано в: :BMC Immunol
Главные авторы: Ni, Guoying, Liao, Zaowen, Chen, Shu, Wang, Tianfang, Yuan, Jianwei, Pan, Xuan, Mounsey, Kate, Cavezza, Shelley, Liu, Xiaosong, Wei, Ming Q.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557397/
https://ncbi.nlm.nih.gov/pubmed/28810829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0224-x
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