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Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking

Legionella pneumophila invades and replicates intracellularly in human and protozoan hosts. The bacteria use the Icm/Dot type IVB secretion system to translocate effectors that inhibit phagosome maturation and modulate host vesicle trafficking pathways. To understand how L. pneumophila modulates org...

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Bibliografiske detaljer
Main Authors: Shohdy, Nadim, Efe, Jem A., Emr, Scott D., Shuman, Howard A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555709/
https://ncbi.nlm.nih.gov/pubmed/15781869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501315102
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