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Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice()

Influenza viral infections often lead to increased mortality in older people. However, the mechanisms by which aging impacts immunity to influenza lung infection remain unclear. We employed a murine model of influenza infection to identify these mechanisms. With aging, we found reduced numbers of al...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Wong, Christine K., Smith, Candice A., Sakamoto, Koji, Kaminski, Naftali, Koff, Jonathan L., Goldstein, Daniel R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557035/
https://ncbi.nlm.nih.gov/pubmed/28646038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700397
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