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The Natural History of Lung Function in Severe Deficiency of Alpha-1 Antitrypsin Following Orthotopic Liver Transplantation: A Case Report

PI*ZZ alpha-1 antitrypsin (AAT) deficiency poses risk for lung disease through 2 different mechanisms: a toxic loss of function in which deficient AAT levels cause a depleted proteolytic screen and, separately, a proinflammatory effect of Z polymers produced both by alveolar macrophages and by the l...

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Detalhes bibliográficos
Publicado no:Chronic Obstr Pulm Dis
Main Authors: Tejwani, Vickram, Wang, Xiao-Feng, Stoller, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: COPD Foundation, Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556825/
https://ncbi.nlm.nih.gov/pubmed/28848851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15326/jcopdf.2.4.2015.0141
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