Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer progression, the influence of tumor stiffness on the endotheli...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Reid, Steven E, Kay, Emily J, Neilson, Lisa J, Henze, Anne‐Theres, Serneels, Jens, McGhee, Ewan J, Dhayade, Sandeep, Nixon, Colin, Mackey, John BG, Santi, Alice, Swaminathan, Karthic, Athineos, Dimitris, Papalazarou, Vasileios, Patella, Francesca, Román‐Fernández, Álvaro, ElMaghloob, Yasmin, Hernandez‐Fernaud, Juan Ramon, Adams, Ralf H, Ismail, Shehab, Bryant, David M, Salmeron‐Sanchez, Manuel, Machesky, Laura M, Carlin, Leo M, Blyth, Karen, Mazzone, Massimiliano, Zanivan, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556271/
https://ncbi.nlm.nih.gov/pubmed/28694244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694912
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