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Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2)

Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In the field of oncology...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Anderson, Lissa C., Håkansson, Maria, Walse, Björn, Nilsson, Carol L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556139/
https://ncbi.nlm.nih.gov/pubmed/28681360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1705-0
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