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Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer

Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis is a promising target in cancer therapy, but tools for its non-invasive quantification are missing. Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Polasek, Miloslav, Yang, Yan, Schühle, Daniel T., Yaseen, Mohammad A., Kim, Young R., Sung, Yu Sub, Guimaraes, Alexander R., Caravan, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556073/
https://ncbi.nlm.nih.gov/pubmed/28808290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08838-6
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