Structure formation during translocon-unassisted co-translational membrane protein folding

Correctly folded membrane proteins underlie a plethora of cellular processes, but little is known about how they fold. Knowledge of folding mechanisms centres on reversible folding of chemically denatured membrane proteins. However, this cannot replicate the unidirectional elongation of the protein...

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Pubblicato in:Sci Rep
Autori principali: Harris, Nicola J., Reading, Eamonn, Ataka, Kenichi, Grzegorzewski, Lucjan, Charalambous, Kalypso, Liu, Xia, Schlesinger, Ramona, Heberle, Joachim, Booth, Paula J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556060/
https://ncbi.nlm.nih.gov/pubmed/28808343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08522-9
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