Enhancing VTA Ca(v)1.3 L-type Ca(2+) channel activity promotes cocaine and mood - related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens

Genetic factors significantly influence susceptibility for substance abuse and mood disorders. Rodent studies have begun to elucidate a role of Ca(v)1.3 L-type Ca(2+) channels in neuropsychiatric-related behaviors, such as addictive and depressive-like behaviors. Human studies have also linked the C...

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Veröffentlicht in:Mol Psychiatry
Hauptverfasser: Martínez-Rivera, Arlene, Hao, Jin, Tropea, Thomas F., Giordano, Thomas P., Kosovsky, Maria, Rice, Richard C., Lee, Amy, Huganir, Richard L., Striessnig, Joerg, Addy, Nii A., Han, Shizhong, Rajadhyaksha, Anjali M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555837/
https://ncbi.nlm.nih.gov/pubmed/28194001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.9
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