Immediate Initiation of Antiretroviral Therapy for HIV Infection Accelerates Bone Loss Relative to Deferring Therapy: Findings from the START Bone Mineral Density Substudy, a Randomized Trial

Both HIV infection and antiretroviral therapy (ART) are associated with lower bone mineral density (BMD) and increased fracture risk. The relative contributions of ART and untreated HIV to BMD loss are unclear, it is important to quantify the effect of ART on bone. We compared the effect of early AR...

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Pubblicato in:J Bone Miner Res
Autori principali: Hoy, Jennifer F, Grund, Birgit, Roediger, Mollie, Schwartz, Ann V, Shepherd, John, Avihingsanon, Anchalee, Badal-Faesen, Sharlaa, de Wit, Stephane, Jacoby, Simone, La Rosa, Alberto, Pujari, Sanjay, Schechter, Mauro, White, David, Engen, Nicole Wyman, Ensrud, Kristine, Aagaard, Peer D, Carr, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555813/
https://ncbi.nlm.nih.gov/pubmed/28650589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3183
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