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Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit

BACKGROUND: Enhanced platelet-derived growth factor receptor α (PDGFRα) signaling pathway activity leads to cardiac fibrosis. However, because of the pleiotropic effects of PDGFR signaling, its role in mediating the cardiac fibrotic response remains poorly understood. This study aimed to investigate...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Wang, Lexun, Yue, Yuan, Yang, Xiao, Fan, Tian, Mei, Bo, Hou, Jian, Liang, Mengya, Chen, Guangxian, Wu, Zhongkai
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555739/
https://ncbi.nlm.nih.gov/pubmed/28780584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.906038
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