Low lamin A expression in lung adenocarcinoma cells from pleural effusions is a pejorative factor associated with high number of metastatic sites and poor Performance status

The type V intermediate filament lamins are the principal components of the nuclear matrix, including the nuclear lamina. Lamins are divided into A-type and B-type, which are encoded by three genes, LMNA, LMNB1, and LMNB2. The alternative splicing of LMNA produces two major A-type lamins, lamin A an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kaspi, Elise, Frankel, Diane, Guinde, Julien, Perrin, Sophie, Laroumagne, Sophie, Robaglia-Schlupp, Andrée, Ostacolo, Kevin, Harhouri, Karim, Tazi-Mezalek, Rachid, Micallef, Joelle, Dutau, Hervé, Tomasini, Pascale, De Sandre-Giovannoli, Annachiara, Lévy, Nicolas, Cau, Pierre, Astoul, Philippe, Roll, Patrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555706/
https://ncbi.nlm.nih.gov/pubmed/28806747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183136
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