Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

GPR116 (ADGRF5) and ELTD1 (ADGRL4) belong to different subfamilies of the adhesion G-protein-coupled receptor group but are both expressed in endothelial cells. We therefore analyzed their functions in mice lacking these receptors. While loss of GPR116 or ELTD1 alone had no obvious effect on cardiov...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Lu, Shun, Liu, Shuya, Wietelmann, Astrid, Kojonazarov, Baktybek, Atzberger, Ann, Tang, Cong, Schermuly, Ralph Theo, Gröne, Hermann-Josef, Offermanns, Stefan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555693/
https://ncbi.nlm.nih.gov/pubmed/28806758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183166
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