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Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Rickettsial infections continue to cause serious morbidity and mortality in severe human cases around the world. Host cell adhesion and invasion is an essential requisite for intracellular growth, replication, and subsequent dissemination of pathogenic rickettsiae. Heparan sulfate proteoglycans [HSP...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sahni, Abha, Patel, Jignesh, Narra, Hema P., Schroeder, Casey L. C., Walker, David H., Sahni, Sanjeev K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555671/
https://ncbi.nlm.nih.gov/pubmed/28806774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183181
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