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Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma

PURPOSE: To delineate the role of Sphingolipids (SPLs) in the human cornea and their cross-talks with transforming growth factor beta (TGF-β) in order to develop novel, non-invasive therapies. METHODS: Human corneal fibroblasts (HCFs) were harvested from healthy donors, stimulated with Vitamin C to...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Nicholas, Sarah E., Rowsey, Tyler G., Priyadarsini, Shrestha, Mandal, Nawajes A., Karamichos, Dimitrios
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555661/
https://ncbi.nlm.nih.gov/pubmed/28806736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182390
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