Antagonism of proteasome inhibitor-induced heme oxygenase-1 expression by PINK1 mutation

PTEN-induced putative kinase 1 (PINK1) is an integral protein in the mitochondrial membrane and maintains mitochondrial fidelity. Pathogenic mutations in PINK1 have been identified as a cause of early-onset autosomal recessive familial Parkinson’s disease (PD). The ubiquitin proteasome pathway is as...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sheng, Xiang-Jun, Tu, Hunag-Ju, Chien, Wei-Lin, Kang, Kai-Hsiang, Lu, Dai-Hua, Liou, Horng-Huei, Lee, Ming-Jen, Fu, Wen-Mei
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555616/
https://ncbi.nlm.nih.gov/pubmed/28806787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183076
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