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– (-) Menthol Induces Reversal of Promoter Hypermethylation and Associated Up-Regulation of the FANCF Gene in the SiHa Cell Line
OBJECTIVE: To identify natural bioactive molecules with potential to inhibit DNA methyltransferase 1 (DNMT1) and cause reactivation of genes silenced due to promoter hypermethylation. METHODS AND RESULTS: -(-) Menthol and epigallocatechin-3-gallate (EGCG) (reference molecule) were investigated using...
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| izdano v: | Asian Pac J Cancer Prev |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
West Asia Organization for Cancer Prevention
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555548/ https://ncbi.nlm.nih.gov/pubmed/28612587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.5.1365 |
| Oznake: |
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