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Antagonism of Acute Sulfide Poisoning in Mice by Nitrite Anion without Methemoglobinemia

There are currently no FDA-approved antidotes for H(2)S/sulfide intoxication. Sodium nitrite, if given prophylactically to Swiss Webster mice, was shown to be highly protective against the acute toxic effects of sodium hydrosulfide (~LD(40) dose) with both agents administered by intraperitoneal inje...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Cronican, Andrea A., Frawley, Kristin L., Ahmed, Humza, Pearce, Linda L., Peterson, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555412/
https://ncbi.nlm.nih.gov/pubmed/25951111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00015
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