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Can Zipf's law be adapted to normalize microarrays?

BACKGROUND: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for varying organisms and tissues have shown that the majority of expressed genes exhibit a power-law distribution with an ex...

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Detalhes bibliográficos
Main Authors: Lu, Tim, Costello, Christine M, Croucher, Peter JP, Häsler, Robert, Deuschl, Günther, Schreiber, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555536/
https://ncbi.nlm.nih.gov/pubmed/15727680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-37
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