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The Metalloporphyrin Co(III)TMPyP Ameliorates Acute, Sub-lethal Cyanide Toxicity in Mice

The formation of Co(III)TMPyP(CN)(2) at pH 7.4 has been shown to be completely cooperative (α(H) = 2) with an association constant of 2.1 (± 0.2) × 10(11). The kinetics were investigated by stopped-flow spectrophotometry and revealed a complicated net reaction exhibiting 4 phases at pH 7.4 under con...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Res Toxicol
Hauptverfasser: Benz, Oscar S., Yuan, Quan, Amoscato, Andrew A., Pearce, Linda L., Peterson, Jim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555306/
https://ncbi.nlm.nih.gov/pubmed/23148604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300327v
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