Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term persistence under conditions of low oxygen tension. Analysis of the Mtb genome predicts the existence of a branched aerobic respiratory chain terminating in a cytochrome bd system and a cytochrome aa(3) system. Both...

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Détails bibliographiques
Auteurs principaux: Weinstein, Edward A., Yano, Takahiro, Li, Lin-Sheng, Avarbock, David, Avarbock, Andrew, Helm, Douglas, McColm, Andrew A., Duncan, Ken, Lonsdale, John T., Rubin, Harvey
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC555520/
https://ncbi.nlm.nih.gov/pubmed/15767566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500469102
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