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Blind SELEX Approach Identifies RNA aptamer that Regulate EMT and Inhibit Metastasis

Identifying targets that are exposed on the plasma membrane of tumor cells, but expressed internally in normal cells, is a fundamental issue for improving the specificity and efficacy of anticancer therpeutics. Using blind cell SELEX (Systemic Evolution of Ligands by EXponetial enrichment) which is...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Yoon, Sorah, Armstrong, Brian, Habib, Nagy, Rossi, John J
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555160/
https://ncbi.nlm.nih.gov/pubmed/28396463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0462
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