HMGB1 redox during sepsis

During sepsis, the alarmin HMGB1 is released from tissues and promotes systemic inflammation that results in multi-organ damage, with the kidney particularly susceptible to injury. The severity of inflammation and pro-damage signaling mediated by HMGB1 appears to be dependent on the alarmin's r...

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Udgivet i:Redox Biol
Main Authors: Abdulmahdi, Wasan, Patel, Devika, Rabadi, May M., Azar, Tala, Jules, Edson, Lipphardt, Mark, Hashemiyoon, Rameen, Ratliff, Brian B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554965/
https://ncbi.nlm.nih.gov/pubmed/28806702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.001
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