Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD

[Image: see text] Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), which can spread its infections to the central nervous and other systems with severe consequences. The viral caspid protein VP1 is a well-known target for antiviral efficacy because its occupa...

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Pubblicato in:ACS Med Chem Lett
Autori principali: Li, Peng, Yu, Jun, Hao, Fei, He, Haiying, Shi, Xuyang, Hu, Jiao, Wang, Li, Du, Chunyan, Zhang, Xiao, Sun, Ya, Lin, Fusen, Gu, Zhengxian, Xu, Deming, Chen, Xinsheng, Shen, Liang, Hu, Guoping, Li, Jian, Chen, Shuhui, Xiao, Wei, Wang, Zhenzhong, Guo, Qingming, Chang, Xiujuan, Tian, Xuyang, Lin, Tianwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554915/
https://ncbi.nlm.nih.gov/pubmed/28835799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00188
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