Mycobacterium bovis Bacillus Calmette–Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function

Intralesional Mycobacterium bovis bacillus Calmette–Guérin (BCG) has long been a relatively inexpensive therapy for inoperable cutaneous metastatic melanoma (CMM), although intralesional BCG skin mechanisms remain understudied. We analyzed intralesional BCG-treated CMM lesions combined with in vitro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lardone, Ricardo D., Chan, Alfred A., Lee, Agnes F., Foshag, Leland J., Faries, Mark B., Sieling, Peter A., Lee, Delphine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554507/
https://ncbi.nlm.nih.gov/pubmed/28848560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00965
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