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Effect of psychotropic drug treatment on sterol metabolism
Cholesterol metabolism is vital for brain function. Previous work in cultured cells has shown that a number of psychotropic drugs inhibit the activity of 7-dehydrocholesterol reductase (DHCR7), an enzyme that catalyzes the final steps in cholesterol biosynthesis. This leads to the accumulation of 7-...
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| Publié dans: | Schizophr Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554466/ https://ncbi.nlm.nih.gov/pubmed/28202290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2017.02.001 |
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