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Effect of psychotropic drug treatment on sterol metabolism

Cholesterol metabolism is vital for brain function. Previous work in cultured cells has shown that a number of psychotropic drugs inhibit the activity of 7-dehydrocholesterol reductase (DHCR7), an enzyme that catalyzes the final steps in cholesterol biosynthesis. This leads to the accumulation of 7-...

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Detalhes bibliográficos
Publicado no:Schizophr Res
Main Authors: Korade, Željka, Liu, Wei, Warren, Emily B., Armstrong, Kristan, Porter, Ned A., Konradi, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554466/
https://ncbi.nlm.nih.gov/pubmed/28202290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2017.02.001
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