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Molecular Pathways: Metabolic control of histone methylation and gene expression in cancer

Epigenetic alterations contribute to tumor development, progression, and therapeutic response. Many epigenetic enzymes use metabolic intermediates as cofactors to modify chromatin structure. Emerging evidence suggests that fluctuation in metabolite levels may regulate activities of these chromatin-m...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Tran, Thai Q., Lowman, Xazmin H., Kong, Mei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553983/
https://ncbi.nlm.nih.gov/pubmed/28404599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2506
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