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Targeting lysyl oxidase reduces peritoneal fibrosis

BACKGROUND: Abdominal surgery and disease cause persistent abdominal adhesions, pelvic pain, infertility and occasionally, bowel obstruction. Current treatments are ineffective and the aetiology is unclear, although excessive collagen deposition is a consistent feature. Lysyl oxidase (Lox) is a key...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Harlow, Christopher R., Wu, Xuan, van Deemter, Marielle, Gardiner, Fiona, Poland, Craig, Green, Rebecca, Sarvi, Sana, Brown, Pamela, Kadler, Karl E., Lu, Yinhui, Mason, J. Ian, Critchley, Hilary O. D., Hillier, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553776/
https://ncbi.nlm.nih.gov/pubmed/28800626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183013
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